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Treosulfan and 4 Gy TBI based conditioning with Rapamycin-based GvHD prophylaxis for allogeneic stem cell transplantation in patients with haematological malignancies

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Trial Profile

Treosulfan and 4 Gy TBI based conditioning with Rapamycin-based GvHD prophylaxis for allogeneic stem cell transplantation in patients with haematological malignancies

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 18 Dec 2018

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At a glance

  • Drugs Treosulfan (Primary) ; Allogeneic stem cell therapy; Antithymocyte globulin; Fludarabine; Mycophenolate mofetil; Rituximab; Sirolimus
  • Indications Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Chronic myeloid leukaemia; Chronic myelomonocytic leukaemia; Graft-versus-host disease; Haematological malignancies; Hodgkin's disease; Multiple myeloma; Myelodysplastic syndromes; Myelofibrosis; Non-Hodgkin's lymphoma
  • Focus Therapeutic Use
  • Acronyms TrRaMM4Gy
  • Most Recent Events

    • 12 Dec 2018 Status changed from recruiting to completed.
    • 10 Dec 2013 Interim results presented at the 55th Annual Meeting and Exposition of the American Society of Hematology.
    • 08 Jun 2012 New trial record

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