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Randomized phase II clinical trial on mRNA electroporated autologous dendritic cells for stage III/IV melanoma in patients who are free from measurable tumor lesions following the local treatment of macro metastases

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Randomized phase II clinical trial on mRNA electroporated autologous dendritic cells for stage III/IV melanoma in patients who are free from measurable tumor lesions following the local treatment of macro metastases

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 01 Jan 2021

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At a glance

  • Drugs TriMix-MEL (Primary) ; TriMix-MEL (Primary)
  • Indications Malignant melanoma
  • Focus Therapeutic Use
  • Acronyms DCMEL

    • Most Recent Events

    • 01 Dec 2020 Due to a lack of financial means to continue the study, patient recruitment was interrupted in October 2014. One year later, following an interim analysis with a minimal follow-up of 1 year for all randomized patients, it was decided to permanently stop the recruitment of patients as per the results published in the Cancer Immunology Immunotherapy.
    • 01 Dec 2020 Results published in the Cancer Immunology Immunotherapy
    • 01 Dec 2020 Status changed from completed to discontinued as per the results published in the Cancer Immunology Immunotherapy.

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