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Phase III, randomized clinical trial to evaluate FOLFOX + bevacizumab versus FOLFOXIRI + bevacizumab as first line treatment of patients with metastatic colorectal cancer not previously treated and with three or more circulating tumoral cells.

Trial Profile

Phase III, randomized clinical trial to evaluate FOLFOX + bevacizumab versus FOLFOXIRI + bevacizumab as first line treatment of patients with metastatic colorectal cancer not previously treated and with three or more circulating tumoral cells.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Bevacizumab (Primary) ; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms VISNU-1

Most Recent Events

  • 04 Jun 2019 Primary endpoint has been met. (Progression free survival (PFS))
  • 04 Jun 2019 Results presented at the 55th Annual Meeting of the American Society of Clinical Oncology
  • 29 Dec 2018 Status changed from active, no longer recruiting to completed.

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