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A Multicenter Randomized Controlled Open-label Trial of Tenofovir Plus Entecavir Combination vs. Tenofovir Monotherapy in Chronic Hepatitis B Patients With Genotypic Resistance to Adefovir and Partial Virologic Response to Ongoing Treatment

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A Multicenter Randomized Controlled Open-label Trial of Tenofovir Plus Entecavir Combination vs. Tenofovir Monotherapy in Chronic Hepatitis B Patients With Genotypic Resistance to Adefovir and Partial Virologic Response to Ongoing Treatment

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 09 Dec 2018

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At a glance

  • Drugs Entecavir (Primary) ; Tenofovir disoproxil fumarate (Primary)
  • Indications Hepatitis B
  • Focus Therapeutic Use

    • Most Recent Events

    • 13 Nov 2018 Results of pooled analysis from NCT01639066 and NCT01639092 assessing whether prolonged TDF monotherapy would be safe and increase the virologic response rate, presented at The Liver Meeting 2018: 69th Annual Meeting of the American Association for the Study of Liver Diseases.
    • 18 Feb 2018 Status changed from active, no longer recruiting to completed.
    • 24 Jun 2015 Planned End Date changed from 1 Jun 2014 to 1 Feb 2018 as reported by ClinicalTrials.gov.

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