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Front-line Treatment of Philadelphia Positive (Ph+)/BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL) With AP24534 (Ponatinib), a New Potent Tyrosine Kinase Inhibitor (TKI).

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Trial Profile

Front-line Treatment of Philadelphia Positive (Ph+)/BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL) With AP24534 (Ponatinib), a New Potent Tyrosine Kinase Inhibitor (TKI).

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 May 2023

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At a glance

  • Drugs Ponatinib (Primary)
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Biomarker; Therapeutic Use
  • Sponsors Incyte Corporation

    • Most Recent Events

    • 19 May 2023 Results evaluating its efficacy ponatinib versus imatinib-based regimens using a matching adjusted indirect comparison from NCT00038610 , NCT00327678, NCT01424982 and NCT01641107 , published in the Advances in Therapy
    • 18 Nov 2021 Status changed from active, no longer recruiting to completed.
    • 02 Feb 2021 Planned End Date changed from 1 Nov 2019 to 31 Dec 2021.

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