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A Randomized, Double-blind, Placebo-controlled Phase III Study of Subcutaneous Secukinumab in Prefilled Syringes to Demonstrate Efficacy at 16 Weeks and to Assess Long-term Efficacy, Safety and Tolerability up to 5 Years in Patients With Active Ankylosing Spondylitis

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Trial Profile

A Randomized, Double-blind, Placebo-controlled Phase III Study of Subcutaneous Secukinumab in Prefilled Syringes to Demonstrate Efficacy at 16 Weeks and to Assess Long-term Efficacy, Safety and Tolerability up to 5 Years in Patients With Active Ankylosing Spondylitis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Jun 2022

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At a glance

  • Drugs Secukinumab (Primary)
  • Indications Ankylosing spondylitis
  • Focus Registrational; Therapeutic Use
  • Acronyms MEASURE 2
  • Sponsors Novartis; Novartis Pharma A.G.; Novartis Pharmaceuticals
  • Most Recent Events

    • 04 Jun 2022 Results of post-hoc analysis evaluating key clinical symptoms at baseline through Wk 260, presented at the 23rd Annual Congress of the European League Against Rheumatism
    • 01 Feb 2022 Results of post-hoc pooled analysis of 3 secukinumab studies (MEASURE 2,-3 &-4) assessing -term NSAID-sparing effect of secukinumab over 4 years in patients with r-axSpA, published in the Rheumatology International.
    • 09 Nov 2021 Results of pooled post-hoc analysis assessing efficacy of secukinumab in patients with oligoarticular PsA by using data from five phase III studies presented at the ACR Convergence 2021
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