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Prospective Controlled Cohort Study on the Safety of a Monophasic Oral Contraceptive Containing Nomegestrol Acetate (2.5mg) and 17beta-estradiol (1.5mg)

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Trial Profile

Prospective Controlled Cohort Study on the Safety of a Monophasic Oral Contraceptive Containing Nomegestrol Acetate (2.5mg) and 17beta-estradiol (1.5mg)

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 13 Apr 2023

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At a glance

  • Drugs Estradiol/nomegestrol (Primary) ; Levonorgestrel; Oral contraceptives
  • Indications Pregnancy
  • Focus Adverse reactions
  • Acronyms INAS-CELINA; PRO-E2

    • Most Recent Events

    • 13 Apr 2023 Results assessing unintended pregnancy and changes in mood, acne, and weight in NOMAC-E2 vs levonorgestrel-containing COC (COCLNG) users under 25 years, published in the Gynecological Endocrinology.
    • 01 Dec 2021 Results assessing the risk of venous thromboembolism (VTE) and arterial thro mboembolism (ATE) in NOMAC-E2 users with levonorgestrel-containing combined oral contraceptive (COCLNG) userspublished in the European Journal of Contraception and Reproductive Health Care
    • 01 Dec 2021 Results published in the European Journal of Contraception and Reproductive Health Care
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