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Integrated Biological Markers for the Prediction of Treatment Response in Depression: A Pilot Study

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Trial Profile

Integrated Biological Markers for the Prediction of Treatment Response in Depression: A Pilot Study

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 27 Dec 2023

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At a glance

  • Drugs Escitalopram (Primary) ; Aripiprazole
  • Indications Major depressive disorder
  • Focus Biomarker; Therapeutic Use
  • Acronyms CAN-BIND-1

    • Most Recent Events

    • 20 Dec 2023 Results assessing SGK1 mRNA expression from peripheral blood, and left and right hippocampal volume at baseline, as well as change in these markers over the first 8 weeks of a 16-week open-label trial of escitalopram as part of the Canadian Biomarker Integration Network in Depression program (MDD [n = 161] and healthy [n = 91] comparison participants, published in the European Neuropsychopharmacology.
    • 15 Nov 2023 Results published in the Journal of Clinical Psychiatry
    • 01 May 2022 Results assessing relationships between antidepressant treatment outcomes and sexual functioning published in the Journal of Psychopharmacology

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