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STRIVE: A MULTICENTER PHASE 2, RANDOMIZED, DOUBLE-BLIND, EFFICACY AND SAFETY STUDY OF ENZALUTAMIDE VS. BICALUTAMIDE IN MEN WITH PROSTATE CANCER WHO HAVE FAILED PRIMARY ANDROGEN DEPRIVATION THERAPY

Trial Profile

STRIVE: A MULTICENTER PHASE 2, RANDOMIZED, DOUBLE-BLIND, EFFICACY AND SAFETY STUDY OF ENZALUTAMIDE VS. BICALUTAMIDE IN MEN WITH PROSTATE CANCER WHO HAVE FAILED PRIMARY ANDROGEN DEPRIVATION THERAPY

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Jul 2022

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At a glance

  • Drugs Enzalutamide (Primary) ; Bicalutamide
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Therapeutic Use
  • Acronyms STRIVE
  • Sponsors Medivation; Pfizer
  • Most Recent Events

    • 25 Aug 2021 Results of a meta-analysis assessing efficacy and safety of treatments for nonmetastatic castration-resistant prostate cancer using patient level data from two studies (IMAAGEN, STRIVE) and aggregate data from other eligible nmCRPC trials presented at the 37th International Conference on Pharmacoepidemiology and Therapeutic Risk Management
    • 20 May 2021 Results of meta analysis of 6 trials including STRIVE and IMAAGEN presented at the 26th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research
    • 08 Apr 2021 Results of meta-analysis of 5 studies (ARN-509-001, PROSPER, STRIVE, ARAMIS, IMAAGEN & SPARTAN), published in the Journal of the National Cancer Institute.
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