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A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When Evolocumab (AMG 145) is Used in Combination With Statin Therapy In Patients With Clinically Evident Cardiovascular Disease

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A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When Evolocumab (AMG 145) is Used in Combination With Statin Therapy In Patients With Clinically Evident Cardiovascular Disease

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 May 2024

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At a glance

  • Drugs Evolocumab (Primary) ; HMG-CoA reductase inhibitors
  • Indications Atherosclerosis; Cardiovascular disorders; Hyperlipidaemia; Myocardial infarction; Stroke
  • Focus Registrational; Therapeutic Use
  • Acronyms FOURIER; PROFICIO
  • Sponsors Amgen

    • Most Recent Events

    • 08 Apr 2024 Results from FOURIER and FOURIER OLE assessing Long-Term Efficacy of Evolocumab in Patients With and Without Multivessel Coronary Artery Disease, presented at the 73rd Annual Scientific Session of the American College of Cardiology
    • 13 Nov 2023 Results from FOURIER and FOURIER OLE assessing Long-Term Efficacy of Evolocumab in Patients With and Without Multivessel Coronary Artery Disease, presented at the American Heart Association Scientific Sessions 2023
    • 10 Nov 2023 Results presented in the Amgen Media Release

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