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A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Evaluate the Efficacy and Safety Of Bevacizumab, and Associated Biomarkers, In Combination With Paclitaxel Compared With Paclitaxel Plus Placebo as First-line Treatment Of Patients With Her2-Negative Metastatic Breast Cancer

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Trial Profile

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Evaluate the Efficacy and Safety Of Bevacizumab, and Associated Biomarkers, In Combination With Paclitaxel Compared With Paclitaxel Plus Placebo as First-line Treatment Of Patients With Her2-Negative Metastatic Breast Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Dec 2021

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At a glance

  • Drugs Bevacizumab (Primary) ; Paclitaxel
  • Indications Adenocarcinoma; Advanced breast cancer; HER2 negative breast cancer; Triple negative breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms Meridian
  • Sponsors Chugai Pharmaceutical; Roche

Most Recent Events

  • 28 Apr 2020 Results (n=1427) assessing the prognostic value of the T effector RNA gene signature (Teff) in four studies (BO20289, NO17629, GO25632 and OAM4861G), presented at the 111th Annual Meeting of the American Association for Cancer Research - I.
  • 02 Jul 2019 This trial has been Discontinued in UK (End date: 2017-11-21) according to European Clinical Trials Database record
  • 24 Apr 2018 This trial has been Discontinued in Belgium (End date: 2017-11-21) according to European Clinical Trials Database record

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