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Randomized, Double-Blind, Double-Dummy, Active-Controlled, Cross-Over Study Evaluating the Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura

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Trial Profile

Randomized, Double-Blind, Double-Dummy, Active-Controlled, Cross-Over Study Evaluating the Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 13 May 2019

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At a glance

  • Drugs Sumatriptan (Primary) ; Sumatriptan
  • Indications Migraine with aura; Migraine without aura
  • Focus Registrational; Therapeutic Use
  • Acronyms COMPASS
  • Sponsors Avanir Pharmaceuticals; OptiNose

    • Most Recent Events

    • 07 May 2019 Results applying novel analytic approach for measuring consistency of response in the acute treatment of episodic migraine using data from the COMPASS study published in the Headache
    • 16 Oct 2017 Results published in the Headache
    • 10 Sep 2017 Results (n=259) comparing efficacy and tolerability of sumatriptan tablets versus sumatriptan delivered intranasally in adult patients with acute migraine with or without aura, were presented at the 2017 International Headache Society.

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