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Randomized, Double-blind, Placebo-controlled, Multicenter Study Comparing Ciprofloxacin DPI 32.5 mg BID (Twice a Day) Intermittently Administered for 28 Days on / 28 Days Off or 14 Days on / 14 Days Off Versus Placebo to Evaluate the Time to First Pulmonary Exacerbation and Frequency of Exacerbations in Subjects With Non-Cystic Fibrosis Bronchiectasis

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Trial Profile

Randomized, Double-blind, Placebo-controlled, Multicenter Study Comparing Ciprofloxacin DPI 32.5 mg BID (Twice a Day) Intermittently Administered for 28 Days on / 28 Days Off or 14 Days on / 14 Days Off Versus Placebo to Evaluate the Time to First Pulmonary Exacerbation and Frequency of Exacerbations in Subjects With Non-Cystic Fibrosis Bronchiectasis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 Apr 2022

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At a glance

  • Drugs Ciprofloxacin (Primary)
  • Indications Bacterial infections; Bronchiectasis
  • Focus Registrational; Therapeutic Use
  • Acronyms RESPIRE-II
  • Sponsors Bayer

    • Most Recent Events

    • 23 May 2018 Results assessing the impact of Exacerbation Definition in RESPIRE 1 and RESPIRE 2 trials, presented at the 114th International Conference of the American Thoracic Society
    • 01 Jan 2018 Results assessing safety and efficacy published in the European Respiratory Journal
    • 24 May 2017 Primary endpoint (Frequency of exacerbation within a 48-week treatment period) has not been met as per the results presented at the 113th International Conference of the American Thoracic Society.

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