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MEA115588 A randomised, double-blind, double-dummy, placebo-controlled, parallel-group, multi-centre study of the efficacy and safety of mepolizumab adjunctive therapy in subjects with severe uncontrolled refractory asthma

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Trial Profile

MEA115588 A randomised, double-blind, double-dummy, placebo-controlled, parallel-group, multi-centre study of the efficacy and safety of mepolizumab adjunctive therapy in subjects with severe uncontrolled refractory asthma

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 12 Jul 2023

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At a glance

  • Drugs Mepolizumab (Primary) ; Mepolizumab (Primary)
  • Indications Asthma; Eosinophilia
  • Focus Registrational; Therapeutic Use
  • Acronyms MENSA
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 24 May 2023 Meta analysis from NCT01000506, NCT01691521, NCT01287039, NCT01285323, NCT01928771, and NCT01914757, presented at the 119th International Conference of the American Thoracic Society.
    • 01 Mar 2021 Results of post hoc meta analysis of data from the Phase III MENSA and MUSCA studies presented at the 2021 Annual Meeting of the American Academy of Allergy, Asthma and Immunology
    • 16 Mar 2020 Results of a post hoc analysis of data from DREAM, MENSA and MUSCA Efficacy of Mepolizumab Stratified by Baseline Blood Eosinophil Count, presented at the 2020 Annual Meeting of the American Academy of Allergy, Asthma and Immunology

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