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A prospective, randomized, open-label, parallel-group, active-controlled, multicenter study exploring the efficacy and safety of once-daily oral rivaroxaban (BAY 59-7939) compared with that of dose-adjusted oral vitamin K antagonist (VKA) for the prevention of stroke and non-central nervous system systemic embolism in subjects with nonvalvular atrial fibrillation scheduled for cardioversion

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Trial Profile

A prospective, randomized, open-label, parallel-group, active-controlled, multicenter study exploring the efficacy and safety of once-daily oral rivaroxaban (BAY 59-7939) compared with that of dose-adjusted oral vitamin K antagonist (VKA) for the prevention of stroke and non-central nervous system systemic embolism in subjects with nonvalvular atrial fibrillation scheduled for cardioversion

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 Nov 2021

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At a glance

  • Drugs Rivaroxaban (Primary) ; Vitamin K antagonists
  • Indications Cardiovascular disorders; Stroke; Thromboembolism
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms X-VeRT
  • Sponsors Bayer
  • Most Recent Events

    • 09 Oct 2021 Results of pre-planned post hoc analysis; assessing whether early cardioversion and high CHADS2 scores predicted sinus rhythm at 6 weeks from cardioversion, published in the Europace
    • 30 Aug 2017 Results from an X-VeRT substudy presented at the ESC Congress 2017: Annual Congress of the European Society of Cardiology
    • 01 Sep 2015 According to a Janssen Pharmaceuticals media release, data from this study were published in the European Heart Journal.

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