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PHASE II RANDOMIZED STUDY OF MAINTENANCE TREATMENT WITH BEVACIZUMAB OR BEVACIZUMAB PLUS METRONOMIC CHEMOTHERAPY AFTER FIRST-LINE INDUCTION FOLFOXIRI PLUS BEVACIZUMAB FOR METASTATIC COLORECTAL CANCER PATIENTS

Trial Profile

PHASE II RANDOMIZED STUDY OF MAINTENANCE TREATMENT WITH BEVACIZUMAB OR BEVACIZUMAB PLUS METRONOMIC CHEMOTHERAPY AFTER FIRST-LINE INDUCTION FOLFOXIRI PLUS BEVACIZUMAB FOR METASTATIC COLORECTAL CANCER PATIENTS

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Feb 2019

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At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine; Cyclophosphamide; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms MOMA
  • Most Recent Events

    • 05 Feb 2019 Results published in the European Journal of Cancer
    • 24 May 2018 Results of an analysis validating loss of chromosome 18q11.2-q12.1, as the predictive factor for survival in patients with metastatic colorectal cancer treated with Bevacizumab using data from three additional multicenter cohorts (Angiopredict cohort, MOMA cohort and NoBev cohort), published in the Journal of Clinical Oncology.
    • 13 Mar 2018 Results of a pooled analysis of five prospective trials ((NCT00719797, NCT02271464, NCT02295930, EudraCT2008-001062-93 and NCT02086656; n=153) assessing prognostic impact of histopathologic parameters, published in the British Journal of Cancer
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