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Phase-III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/neu Negative Breast Cancer

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Phase-III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/neu Negative Breast Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 30 Dec 2024

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At a glance

  • Drugs Everolimus (Primary) ; Anastrozole; Exemestane; Goserelin; Goserelin; Letrozole; Leuprorelin; Leuprorelin; Tamoxifen
  • Indications Early breast cancer; HER2 negative breast cancer; Male breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 10 Dec 2022 Results (n=1792) assessing the efficacy of everolimus in combination with ET in the adjuvant settingamong patients with high-risk hormone receptor-positive, HER2-negative BC presented at the 45th Annual San Antonio Breast Cancer Symposium
    • 20 Jun 2019 Status changed from recruiting to active, no longer recruiting.
    • 26 Jan 2016 Planned number of patients changed from 3500 to 1900, according to ClinicalTrials.gov record.

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