A Phase 1b Dose De-escalation Trial of the Cyclin-dependent Kinase Inhibitor Dinaciclib in Combination With Pembrolizumab in Patients With Advanced Breast Cancer and Assessment of MYC Oncogene Overexpression

Trial Profile

A Phase 1b Dose De-escalation Trial of the Cyclin-dependent Kinase Inhibitor Dinaciclib in Combination With Pembrolizumab in Patients With Advanced Breast Cancer and Assessment of MYC Oncogene Overexpression

Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Apr 2018

At a glance

  • Drugs Dinaciclib (Primary) ; Pembrolizumab (Primary)
  • Indications Advanced breast cancer; Male breast cancer
  • Focus Adverse reactions
  • Most Recent Events

    • 16 Apr 2018 Planned End Date changed from 1 Aug 2018 to 1 Aug 2019.
    • 16 Apr 2018 Planned primary completion date changed from 1 Jun 2018 to 1 Jun 2019.
    • 10 Jun 2017 Biomarkers information updated
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