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An Open-label, Fixed-sequence, Three-period, Single Group Study to Investigate the Effects of Rifampicin as an OATP1B1 Inhibitor and a CYP2C8 Inducer on the Pharmacokinetics of Aleglitazar in Healthy Subjects

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Trial Profile

An Open-label, Fixed-sequence, Three-period, Single Group Study to Investigate the Effects of Rifampicin as an OATP1B1 Inhibitor and a CYP2C8 Inducer on the Pharmacokinetics of Aleglitazar in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Aleglitazar (Primary) ; Rifampicin
  • Indications Cardiovascular disorders; Tuberculosis; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Roche
  • Most Recent Events

    • 23 May 2013 Actual end date changed from Apr 2013 to Dec 2012 as reported by ClinicalTrials.gov.
    • 14 Jan 2013 Status changed from not yet recruiting to completed as reported by ClinicalTrials.gov.
    • 13 Sep 2012 New trial record

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