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A phase II randomised trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) vs cyclophosphamide, velcade and dexamethasone (CVD) for first relapse or primary refractory multiple myeloma

Trial Profile

A phase II randomised trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) vs cyclophosphamide, velcade and dexamethasone (CVD) for first relapse or primary refractory multiple myeloma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Dec 2018

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At a glance

  • Drugs Carfilzomib (Primary) ; Cyclophosphamide (Primary) ; Dexamethasone (Primary) ; Bortezomib
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms MUK-five
  • Most Recent Events

    • 04 Dec 2018 Results based on genetic risk and long term follow up of the phase 2 Muk Five trial presented at the 60th Annual Meeting and Exposition of the American Society of Hematology
    • 04 Dec 2018 Primary endpoint (Progression-free survival) has been met, according to the results presented at the 60th Annual Meeting and Exposition of the American Society of Hematology
    • 04 Dec 2018 Results presented at the 60th Annual Meeting and Exposition of the American Society of Hematology
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