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Phase I Study of the Combination of Trastuzumab Emtansine (T-DM1) and Capecitabine in HER2-Positive Metastatic Breast Cancer and HER2-Positive Locally Advanced/Metastatic Gastric Cancer Patients, Followed by a Randomized, Open-Label Phase II Study of Trastuzumab Emtansine and Capecitabine Versus Trastuzumab Emtansine Alone in HER2-Positive Metastatic Breast Cancer

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Trial Profile

Phase I Study of the Combination of Trastuzumab Emtansine (T-DM1) and Capecitabine in HER2-Positive Metastatic Breast Cancer and HER2-Positive Locally Advanced/Metastatic Gastric Cancer Patients, Followed by a Randomized, Open-Label Phase II Study of Trastuzumab Emtansine and Capecitabine Versus Trastuzumab Emtansine Alone in HER2-Positive Metastatic Breast Cancer

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 23 Dec 2021

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At a glance

  • Drugs Capecitabine (Primary) ; Trastuzumab emtansine (Primary)
  • Indications Advanced breast cancer; Gastric cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TRAXHER2
  • Sponsors Roche
  • Most Recent Events

    • 18 Dec 2021 This trial has been completed in Italy, according to European Clinical Trials Database record.
    • 25 Aug 2017 Status changed from active, no longer recruiting to completed.
    • 18 Jul 2017 The trial has been completed in Greece. (end date: 2017-05-31).
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