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A Phase III, Double-Blind, Placebo-Controlled Study of Vemurafenib Versus Vemurafenib Plus GDC-0973 in Previously Untreated BRAF^600-Mutation Positive Patients With Unresectable Locally Advanced or Metastatic Melanoma

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Trial Profile

A Phase III, Double-Blind, Placebo-Controlled Study of Vemurafenib Versus Vemurafenib Plus GDC-0973 in Previously Untreated BRAF^600-Mutation Positive Patients With Unresectable Locally Advanced or Metastatic Melanoma

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2022

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At a glance

  • Drugs Cobimetinib (Primary) ; Vemurafenib (Primary)
  • Indications Malignant melanoma
  • Focus Registrational; Therapeutic Use
  • Acronyms coBRIM
  • Sponsors Genentech; Roche

    • Most Recent Events

    • 30 Oct 2022 Results of pooled analysis form NCT03178851, NCT01689519, NCT02322814, and NCT02788279 of safety analysis, published in the Drug Safety
    • 23 Dec 2021 This trial has been completed in Italy, according to European Clinical Trials Database record.
    • 18 Dec 2021 This trial has been completed in Italy, according to European Clinical Trials Database record.

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