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A Phase I, 2-Panel, Open-Label Study in Healthy Subjects to Investigate the Pharmacokinetic Interaction Between TMC435 and the HMG-CoA Reductase Inhibitors Atorvastatin and Simvastatin

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Trial Profile

A Phase I, 2-Panel, Open-Label Study in Healthy Subjects to Investigate the Pharmacokinetic Interaction Between TMC435 and the HMG-CoA Reductase Inhibitors Atorvastatin and Simvastatin

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 30 Nov 2012

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At a glance

  • Drugs Simeprevir (Primary) ; Atorvastatin; Simvastatin
  • Indications Cardiovascular disorders; Cystic fibrosis; Diabetic cardiomyopathy; Diabetic nephropathies; Heart failure; Hepatitis C; Hypercholesterolaemia; Hyperlipoproteinaemia; Hyperlipoproteinaemia type II; Hyperlipoproteinaemia type III; Hypertriglyceridaemia; Low HDL cholesterol
  • Focus Pharmacokinetics

Most Recent Events

  • 24 Sep 2012 New trial record

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