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A Phase IIa, Open-label Trial to Evaluate the Safety, Tolerability and Efficacy of a 12 Weeks Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Chronic Genotype 1 Hepatitis C Infected Patients

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A Phase IIa, Open-label Trial to Evaluate the Safety, Tolerability and Efficacy of a 12 Weeks Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Chronic Genotype 1 Hepatitis C Infected Patients

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 27 Feb 2017

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At a glance

  • Drugs JNJ 56914845 (Primary) ; Simeprevir (Primary) ; TMC 647055 (Primary) ; Ribavirin; Ritonavir; Ritonavir
  • Indications Hepatitis C
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Sponsors Janssen Research & Development

    • Most Recent Events

    • 10 Feb 2017 Results published in the BMC Gastroenterology
    • 16 Mar 2015 Results published in Medivir AB media release.
    • 25 Jan 2015 Status changed from active, no longer recruiting to completed, as reported by ClinicalTrials.gov.

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