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A Multicenter, Open Label, Randomized Phase II Trial of the MEK Inhibitor Pimasertib or Dacarbazine in Previously Untreated Subjects With N-Ras Mutated Locally Advanced or Metastatic Malignant Cutaneous Melanoma.

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Trial Profile

A Multicenter, Open Label, Randomized Phase II Trial of the MEK Inhibitor Pimasertib or Dacarbazine in Previously Untreated Subjects With N-Ras Mutated Locally Advanced or Metastatic Malignant Cutaneous Melanoma.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Pimasertib (Primary) ; Dacarbazine
  • Indications Malignant melanoma; Skin cancer
  • Focus Therapeutic Use
  • Sponsors EMD Serono; Merck Serono

    • Most Recent Events

    • 11 Oct 2016 Primary endpoint (Progression-free survival) has been met, according to results presented at the 41st European Society for Medical Oncology Congress.
    • 11 Oct 2016 Results assessing safety and efficacy presented at the 41st European Society for Medical Oncology Congress.
    • 11 Feb 2016 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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