Trial Profile

A Phase I Study of MLN8237 in Combination With Bortezomib and Rituximab in Relapsed and Refractory Mantle Cell and Low Grade Non-Hodgkin Lymphoma

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 18 Mar 2026

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At a glance

Drugs Alisertib (Primary) ; Bortezomib (Primary) ; Rituximab
Indications B-cell lymphoma; Mantle-cell lymphoma; Non-Hodgkin's lymphoma
Focus Adverse reactions

Most Recent Events

05 Mar 2026 Planned End Date changed from 19 Mar 2026 to 3 Mar 2027.
21 Mar 2025 Planned End Date changed from 5 Mar 2025 to 19 Mar 2026.
04 Dec 2018 Results assessing safety and efficacy of Alisertib in combination with bortezomib and rituximab in Relapsed and Refractory Mantle Cell and Low Grade Non-Hodgkin Lymphoma presented at the 60th Annual Meeting and Exposition of the American Society of Hematology

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