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Phase I Study of Escalated Pharmacologic Dose, of Oral Folinic Acid in Combination With Temozolomide, According to Stupp R. Regimen, in Patients With Operated Grade-IV Astocytoma and a Non-methylated Gene Status of MGMT

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Trial Profile

Phase I Study of Escalated Pharmacologic Dose, of Oral Folinic Acid in Combination With Temozolomide, According to Stupp R. Regimen, in Patients With Operated Grade-IV Astocytoma and a Non-methylated Gene Status of MGMT

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 23 Feb 2023

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At a glance

  • Drugs Folinic acid (Primary) ; Temozolomide (Primary)
  • Indications Glioblastoma
  • Focus Adverse reactions; Pharmacogenomic
  • Acronyms FOLAGLI
  • Most Recent Events

    • 20 May 2021 Status changed from recruiting to discontinued.
    • 21 Sep 2020 Results presented at the 45th European Society for Medical Oncology Congress
    • 01 Jan 2013 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov record.

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