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An integrated Phase I/IIa study to evaluate the safety, tolerability and pharmacokinetics of single ascending doses of inhaled GRC 17536 in healthy adult volunteers and multiple ascending doses in patients with mild asthma; and randomised, double-blind, placebo controlled, cross-over study to evaluate the effects of multiple doses of inhaled GRC 17536 on late phase asthmatic response to allergen challenge in patients with mild asthma.

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Trial Profile

An integrated Phase I/IIa study to evaluate the safety, tolerability and pharmacokinetics of single ascending doses of inhaled GRC 17536 in healthy adult volunteers and multiple ascending doses in patients with mild asthma; and randomised, double-blind, placebo controlled, cross-over study to evaluate the effects of multiple doses of inhaled GRC 17536 on late phase asthmatic response to allergen challenge in patients with mild asthma.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 May 2014

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At a glance

  • Drugs ISC 17536 (Primary)
  • Indications Asthma
  • Focus Adverse reactions; Pharmacodynamics; Therapeutic Use
  • Sponsors Glenmark Pharmaceuticals S.A.
  • Most Recent Events

    • 26 Mar 2014 Status changed from recruiting to completed as reported byEuropean Clinical Trials Database.
    • 30 Oct 2012 New trial record

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