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Top-down Infliximab Study in Kids With Crohn's Disease

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Trial Profile

Top-down Infliximab Study in Kids With Crohn's Disease

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 08 Mar 2024

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At a glance

  • Drugs Infliximab (Primary) ; Azathioprine; Prednisolone
  • Indications Crohn's disease
  • Focus Therapeutic Use
  • Acronyms TISKids
  • Most Recent Events

    • 04 Mar 2024 Status changed from active, no longer recruiting to completed.
    • 11 Oct 2022 Results assessing whether combination therapy has pharmacokinetic benefits over proactive therapeutic drug monitoring mono therapy Infliximab, comparing drug exposure expressed as area under concentration curve (AUC), trough concentrations (TL) and IFX clearance (CL) between combo and proactive therapeutic drug monitoring mono Infliximab treated patients, presented at the 30th United European Gastroenterology Week.
    • 01 Aug 2022 Results (n=47) assessing the proportion of patients in which EEN or corticosteroids induced remission and maintained remission on azathioprine monotherapy, published in the European Journal of Pediatrics.

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