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Phase IIIb Study Minimizing Adverse Haemmhorragic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX)

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Trial Profile

Phase IIIb Study Minimizing Adverse Haemmhorragic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 Sep 2023

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At a glance

  • Drugs Bivalirudin (Primary) ; Abciximab; Eptifibatide; Heparin; Tirofiban
  • Indications Acute coronary syndromes; Cardiovascular disorders
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms MATRIX; MATRIX-Access

    • Most Recent Events

    • 25 Sep 2023 Results of Individual Patient Data Meta-Analysis , from MATRIX, VALIDATE-SWEDEHEART, ISAR-REACT 4, ACUITY and BRIGHT; comparing the outcomes of bivalirudin and heparin in patients with non-ST-segment-elevation myocardial infarction undergoing PCI, published in the Circulation
    • 07 Nov 2022 Results of pooled subgroup analysis (n=15254) assessing efficacy of bivalirudin versus heparin in patients with STEMI undergoing PCI from BRIGHT, EUROMAX, HEAT-PPCI, HORIZONS-AMI, MATRIX, and VALIDATE-SWEDEHEART studies, presented at the American Heart Association Scientific Sessions 2022.
    • 02 Feb 2021 Results assessing incidence, predictors, effects on randomized treatments, and prognostic implications of in hospital hemoglobin drop in patients with and without adjudicated overt bleeding using data from Matrix trial published in the Journal of the American College of Cardiology

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