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A Randomised, Double-blind, Placebo-controlled Study to Evaluate the Effect on Urine Albumin-to-Creatinine Ratio (UACR), Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of Multiple Oral Doses of MT-3995 as Add-on Therapy to ACE-I or ARB in Type II Diabetic Nephropathy Subjects with Albuminuria and an eGFR ≥60 mL/min/1.73m2

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A Randomised, Double-blind, Placebo-controlled Study to Evaluate the Effect on Urine Albumin-to-Creatinine Ratio (UACR), Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of Multiple Oral Doses of MT-3995 as Add-on Therapy to ACE-I or ARB in Type II Diabetic Nephropathy Subjects with Albuminuria and an eGFR ≥60 mL/min/1.73m2

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Apr 2023

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At a glance

  • Drugs Apararenone (Primary) ; ACE inhibitors; Angiotensin receptor antagonists
  • Indications Diabetic nephropathies; Hypertension
  • Focus Adverse reactions; Pharmacodynamics
  • Sponsors Mitsubishi Tanabe Pharma Corporation

    • Most Recent Events

    • 08 Feb 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 25 Sep 2014 Planned End Date changed from 1 Dec 2013 to 1 Nov 2014 as reported by ClinicalTrials.gov.
    • 25 Sep 2014 Planned primary completion date changed from 1 Dec 2013 to 1 Nov 2014 as reported by ClinicalTrials.gov.

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