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LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

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Trial Profile

LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Sep 2023

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At a glance

  • Drugs Dabrafenib (Primary) ; Trametinib (Primary)
  • Indications Malignant melanoma
  • Focus Pharmacodynamics; Pharmacogenomic

    • Most Recent Events

    • 07 Nov 2018 Status changed from active, no longer recruiting to completed.
    • 01 Mar 2018 Planned End Date changed from 1 Apr 2018 to 1 Nov 2018.
    • 31 May 2017 Planned End Date changed from 1 Apr 2017 to 1 Apr 2018.

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