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A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLINDED, ASCENDING MULTIPLE DOSE STUDY OF THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF XMAB 5871 IN PATIENTS WITH RHEUMATOID ARTHRITIS

Trial Profile

A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLINDED, ASCENDING MULTIPLE DOSE STUDY OF THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF XMAB 5871 IN PATIENTS WITH RHEUMATOID ARTHRITIS

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 02 Jan 2024

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At a glance

  • Drugs Obexelimab (Primary)
  • Indications Immunoglobulin G4-related disease; Rheumatoid arthritis
  • Focus Adverse reactions
  • Sponsors Xencor

Most Recent Events

  • 15 Nov 2023 Results of a PopPK model analysis from four clinical trials: a first-in-human, single-ascending dose study in healthy volunteers; 2) a multiple-ascending dose study in patients with RA; 3) an open-label study in patients with IgG4-RD; and 4) a PK and relative bioavailability study.
  • 09 Nov 2015 According to a Xencor media release, data from this study were presented at the American College of Rheumatology (ACR) 2015 Annual Meeting.
  • 26 Jun 2015 According to a Xencor media release, data from this study were presented at the European League Against Rheumatism (EULAR) 2015 Annual Meeting.

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