A Phase Ib, Open-label, Multi-center, Two-arm, Dose-finding Study to Assess Safety and Efficacy of the Oral Combination or INC424 (INC424) and BKM120 in Patients With Primary Myelofibrosis (PMF), Postpolycythemia Vera-myelofibrosis (PPV-MF), or Post-essential Thrombocythemia-myelofibrosis (PET-MF)

Status: Discontinued

Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

Drugs Buparlisib (Primary) ; Ruxolitinib (Primary)
Indications Myelofibrosis
Focus Adverse reactions
Acronyms HARMONY
Sponsors Novartis Pharmaceuticals

Most Recent Events

06 Mar 2019 Status changed from completed to discontinued.
13 Nov 2017 Status changed from active, no longer recruiting to completed.
17 Jul 2017 Planned End Date changed from 1 Dec 2018 to 1 Sep 2017.

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