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A Phase 1b/2, Multicenter, Open-label Trial to Evaluate the Safety and Efficacy of Talimogene Laherparepvec and Ipilimumab Compared to Ipilimumab Alone in Subjects With Unresected, Stage IIIB-IV Melanoma

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A Phase 1b/2, Multicenter, Open-label Trial to Evaluate the Safety and Efficacy of Talimogene Laherparepvec and Ipilimumab Compared to Ipilimumab Alone in Subjects With Unresected, Stage IIIB-IV Melanoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 11 Mar 2022

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At a glance

  • Drugs Talimogene laherparepvec (Primary) ; Ipilimumab
  • Indications Malignant melanoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Amgen

    • Most Recent Events

    • 28 Mar 2021 This trial has been completed in Germany (Global End Date: 09 Mar 2021), according to European Clinical Trials Database record.
    • 23 Mar 2021 Status changed from active, no longer recruiting to completed.
    • 31 May 2020 Results of post hoc analysis (As of February 25, 2019) evaluating Association between complete response and survival in advanced melanoma treated with talimogene laherparepvec (T-VEC) plus ipilimumab, presented at the 56th Annual Meeting of the American Society of Clinical Oncology

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