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An Adaptive Phase I/II Study of the Safety of CD4+ T Lymphocytes and CD34+ Hematopoietic Stem/Progenitor Cells Transduced With LVsh5/C46, a Dual Anti-HIV Gene Transfer Construct, With and Without Conditioning With Busulfan in HIV-1 Infected Adults Previously Exposed to ART

Trial Profile

An Adaptive Phase I/II Study of the Safety of CD4+ T Lymphocytes and CD34+ Hematopoietic Stem/Progenitor Cells Transduced With LVsh5/C46, a Dual Anti-HIV Gene Transfer Construct, With and Without Conditioning With Busulfan in HIV-1 Infected Adults Previously Exposed to ART

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 04 Oct 2018

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At a glance

  • Drugs Cal 1 (Primary) ; Cal-1 transduced T cells (Primary) ; Busulfan
  • Indications HIV-1 infections
  • Focus Adverse reactions; Pharmacogenomic
  • Sponsors Calimmune
  • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 06 Feb 2018 Status changed from active, no longer recruiting to completed.
    • 28 Nov 2016 Planned End Date changed from 1 Sep 2017 to 1 Oct 2017.
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