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An Open-label, Single-dose Study of the Safety, Tolerability, and Pharmacokinetics of AMG 423 in Healthy Subjects and Subjects With Various Degrees of Renal Insufficiency and Effect of Hemodialysis on AMG 423 Pharmacokinetics

Trial Profile

An Open-label, Single-dose Study of the Safety, Tolerability, and Pharmacokinetics of AMG 423 in Healthy Subjects and Subjects With Various Degrees of Renal Insufficiency and Effect of Hemodialysis on AMG 423 Pharmacokinetics

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Omecamtiv mecarbil (Primary)
  • Indications Heart failure
  • Focus Pharmacokinetics
  • Sponsors Amgen; Cytokinetics

Most Recent Events

  • 17 Sep 2021 Results presented at the 2021 American College of Clinical Pharmacology Annual Meeting
  • 26 Mar 2021 Results published in the Clinical Pharmacokinetics.
  • 26 Mar 2021 Status changed from recruiting to completed.

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