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A Phase I/II Study of Lymphodepletion Plus Adoptive Cell Transfer With T-Cells Transduced With CXCR2 and Nerve Growth Factor Receptor (NGFR) Followed by High Dose Interleukin-2 in Patients With Metastatic Melanoma

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Trial Profile

A Phase I/II Study of Lymphodepletion Plus Adoptive Cell Transfer With T-Cells Transduced With CXCR2 and Nerve Growth Factor Receptor (NGFR) Followed by High Dose Interleukin-2 in Patients With Metastatic Melanoma

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs CXCR2-transduced T cells (Primary) ; NGFR-transduced T cells (Primary) ; Aldesleukin; Cyclophosphamide; Fludarabine; Mesna
  • Indications Malignant melanoma
  • Focus Adverse reactions

    • Most Recent Events

    • 17 Feb 2020 Biomarkers information updated
    • 09 Dec 2013 Planned End Date changed from 1 Dec 2018 to 1 Apr 2019 as reported by ClinicalTrials.gov.
    • 09 Dec 2013 Planned initiation date changed from 1 Dec 2013 to 1 Apr 2014 as reported by ClinicalTrials.gov.

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