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A Phase 1/2 Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-414 in Subjects With Advanced Solid Tumours Likely to Over-Express the Epidermal Growth Factor Receptor (EGFR)

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Trial Profile

A Phase 1/2 Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-414 in Subjects With Advanced Solid Tumours Likely to Over-Express the Epidermal Growth Factor Receptor (EGFR)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Depatuxizumab mafodotin (Primary)
  • Indications Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man; Pharmacokinetics; Therapeutic Use
  • Sponsors AbbVie
  • Most Recent Events

    • 13 Mar 2018 According to results published in the Cancer, study was designed as a phase 1 and 2 however, the study sponsor ultimately decided not to extend the study into the phase 2 expansion cohort, and no patients were enrolled in that phase.
    • 13 Mar 2018 Results assessing the safety, pharmacokinetics, and efficacy of depatux-m in patients who had advanced solid tumors, were published in the Cancer.
    • 07 Jan 2016 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
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