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A Phase I Study of Single-agent AZD1775 (MK-1775), a Wee1 Inhibitor, in Patients With Advanced Refractory Solid Tumors

Trial Profile

A Phase I Study of Single-agent AZD1775 (MK-1775), a Wee1 Inhibitor, in Patients With Advanced Refractory Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Adavosertib (Primary)
  • Indications Endometrial cancer; Ovarian cancer; Solid tumours
  • Focus Adverse reactions; Pharmacokinetics
  • Most Recent Events

    • 16 Apr 2021 Results (n=42) from once-daily arm of this study assessing Safety, anti-tumor activity, and biomarker analysis published in the Clinical Cancer Research
    • 31 May 2020 Results (n=35) assessing potential biomarkers of response from tumor genomic analysis in patients with solid tumors treated with adavosertib, presented at the 56th Annual Meeting of the American Society of Clinical Oncology.
    • 20 May 2020 Status changed from active, no longer recruiting to completed.
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