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Randomized, Double-Blind, Placebo Controlled Phase II Study of FOLFOX +/- Ziv-Aflibercept in Patients With Advanced Esophageal and Gastric Cancer

Trial Profile

Randomized, Double-Blind, Placebo Controlled Phase II Study of FOLFOX +/- Ziv-Aflibercept in Patients With Advanced Esophageal and Gastric Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 26 Mar 2019

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At a glance

  • Drugs Aflibercept (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use
  • Acronyms ZAMEGA
  • Most Recent Events

    • 26 Mar 2019 Results assessing efficacy of mFOLFOX6 and Ziv-Aflibercept in patients with first-line metastatic gastroesopheageal adenocarcinoma published in the Cancer
    • 26 Mar 2019 Primary endpoint (6-month Progression-free Survival (PFS)) has not been met published in the Cancer.
    • 05 Apr 2018 Status changed from active, no longer recruiting to completed.
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