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Pediatric Neuro-Oncology Consortium (PNOC)-002: Safety, Phase 0, and Pilot Efficacy Study of Vemurafenib, an Oral Inhibitor of BRAFV600E, in Children and Young Adults With Recurrent/Refractory BRAFV600E- or BRAF Ins T Mutant Brain Tumors

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Trial Profile

Pediatric Neuro-Oncology Consortium (PNOC)-002: Safety, Phase 0, and Pilot Efficacy Study of Vemurafenib, an Oral Inhibitor of BRAFV600E, in Children and Young Adults With Recurrent/Refractory BRAFV600E- or BRAF Ins T Mutant Brain Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase 0

Latest Information Update: 19 Jan 2024

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At a glance

  • Drugs Vemurafenib (Primary)
  • Indications Astrocytoma; Glioma
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use

    • Most Recent Events

    • 16 Jan 2024 Planned End Date changed from 31 Dec 2023 to 31 Dec 2025.
    • 04 Jan 2023 Planned End Date changed from 31 Dec 2022 to 31 Dec 2023.
    • 09 Aug 2022 Status changed to active, no longer recruiting.

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