A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of VX-509 Using Magnetic Resonance Imaging and Arthroscopic Biopsies in Subjects With Active Rheumatoid Arthritis on Stable Disease-Modifying Antirheumatic Drugs
Latest Information Update: 07 Nov 2021
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At a glance
- Drugs Decernotinib (Primary)
- Indications Rheumatoid arthritis
- Focus Therapeutic Use
- Sponsors Vertex Pharmaceuticals
- 15 Apr 2016 Primary endpoint of change from baseline in OMERACT RAMRIS bone marrow edema (osteitis) in designated hand wrist has been met according to results published in the Annals of the Rheumatic Diseases.
- 15 Apr 2016 Primary endpoint of change from baseline in OMERACT RAMRIS synovitis score in designated hand wrist has been met according to results published in the Annals of the Rheumatic Diseases.
- 15 Apr 2016 Primary endpoint of change from baseline in Disease Activity Score 28 using CRP has been met according to results published in the Annals of the Rheumatic Diseases.