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A Phase 3, Randomized, Placebo-controlled, Parallel-Group, Multicenter, Double-blind Study to Evaluate the Efficacy and Safety of Telotristat Etiprate (LX1606) in Patients with Carcinoid Syndrome not adequately controlled by Somatostatin Analog (SSA) Therapy

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Trial Profile

A Phase 3, Randomized, Placebo-controlled, Parallel-Group, Multicenter, Double-blind Study to Evaluate the Efficacy and Safety of Telotristat Etiprate (LX1606) in Patients with Carcinoid Syndrome not adequately controlled by Somatostatin Analog (SSA) Therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Oct 2021

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At a glance

  • Drugs Telotristat etiprate (Primary)
  • Indications Malignant carcinoid syndrome
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms TELESTAR
  • Sponsors Lexicon Pharmaceuticals
  • Most Recent Events

    • 28 Sep 2021 Results of pooled analysis of two phase III clinical TELESTAR and TELECAST trials assessing weight changes and nutritional metabolic disorder status, including cholesterol and albumin concentrations published in the Clinical Therapeutics
    • 11 Mar 2020 A model was developed to evaluate the 5-year budget impact of introducing telotristat ethyl to standard care in Swedish patients with uncontrolled carcinoid syndrome ;results published in the PharmacoEconomics
    • 19 Jan 2019 Results assessing the patient-reported outcomes, presented at the 2019 Gastrointestinal Cancers Symposium

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