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Phase Ib Multicenter, Cohort Dose Escalation Trial to Determine the Safety, Tolerance and Preliminary Antineoplastic Activity of Gemcitabine Administered in Combination With Continuous Intravenous Doses of PRI-724, a CBP/ beta-Catenin Inhibitor, to Patients With Advanced or Metastatic Pancreatic Adenocarcinoma Eligible for Second-Line Therapy After Failing First-Line Therapy With FOLFIRINOX (or FOLFOX)

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Trial Profile

Phase Ib Multicenter, Cohort Dose Escalation Trial to Determine the Safety, Tolerance and Preliminary Antineoplastic Activity of Gemcitabine Administered in Combination With Continuous Intravenous Doses of PRI-724, a CBP/ beta-Catenin Inhibitor, to Patients With Advanced or Metastatic Pancreatic Adenocarcinoma Eligible for Second-Line Therapy After Failing First-Line Therapy With FOLFIRINOX (or FOLFOX)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Foscenvivint (Primary) ; Gemcitabine (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Adverse reactions
  • Sponsors PRISM Pharma Co
  • Most Recent Events

    • 20 Oct 2015 Status changed from recruiting to completed as reported by ClinicalTrials.gov record.
    • 17 Jun 2015 Planned End Date changed from 1 Jun 2015 to 1 Mar 2016 as per ClinicalTrials.gov record.
    • 17 Jun 2015 Planned primary completion date changed from 1 Apr 2015 to 1 Mar 2016 as per ClinicalTrials.gov record.

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