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A Phase 1, Open-Label Study to Examine the Effect of Ciprofloxacin, Itraconazole, and Rifampin on the Pharmacokinetics of Lumacaftor in Combination With Ivacaftor in Healthy Adult Subjects

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Trial Profile

A Phase 1, Open-Label Study to Examine the Effect of Ciprofloxacin, Itraconazole, and Rifampin on the Pharmacokinetics of Lumacaftor in Combination With Ivacaftor in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 19 Nov 2013

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At a glance

  • Drugs Ivacaftor (Primary) ; Lumacaftor (Primary) ; Ciprofloxacin; Itraconazole; Rifampicin
  • Indications Bacterial infections; Cystic fibrosis
  • Focus Pharmacokinetics; Therapeutic Use

    • Most Recent Events

    • 14 Nov 2013 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 20 Sep 2013 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov record.
    • 24 Jul 2013 Planned number of patients changed from 54 to 78 as reported by ClinicalTrials.gov record.

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