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Relative Bioavailability of a Single Oral Dose of Nintedanib Given Alone and in Combination With Multiple Oral Doses of Rifampicin in Healthy Male Volunteers (an Open-label, Two-period, Fixed Sequence Phase I Trial)

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Relative Bioavailability of a Single Oral Dose of Nintedanib Given Alone and in Combination With Multiple Oral Doses of Rifampicin in Healthy Male Volunteers (an Open-label, Two-period, Fixed Sequence Phase I Trial)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Mar 2018

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At a glance

  • Drugs Nintedanib (Primary) ; Rifampicin (Primary)
  • Indications Cancer; Mycobacterial infections
  • Focus Pharmacokinetics
  • Sponsors Boehringer Ingelheim Pharmaceuticals

    • Most Recent Events

    • 02 Mar 2018 Results investigating the effects of ketoconazole, a p-glycoprotein inhibitor, and rifampicin, a p-glycoprotein inducer, on the pharmacokinetics of nintedanib from 2 trials (NCT01679613, NCT01770392) published in the European Journal of Drug Metabolism and Pharmacokinetics
    • 01 Mar 2013 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 29 Jan 2013 New trial record

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