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A Single-arm, Multicenter, Nilotinib Treatment-free Remission Study in Patients With BCR-ABL1 Positive Chronic Myelogenous Leukemia in Chronic Phase Who Have Achieved Durable Minimal Residual Disease (MRD) Status on First Line Nilotinib Treatment

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A Single-arm, Multicenter, Nilotinib Treatment-free Remission Study in Patients With BCR-ABL1 Positive Chronic Myelogenous Leukemia in Chronic Phase Who Have Achieved Durable Minimal Residual Disease (MRD) Status on First Line Nilotinib Treatment

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 30 Dec 2024

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At a glance

  • Drugs Nilotinib (Primary)
  • Indications Chronic myeloid leukaemia
  • Focus Registrational; Therapeutic Use
  • Acronyms ENESTFreedom
  • Sponsors Novartis; Novartis Farma; Novartis Pharma A.G.; Novartis Pharmaceuticals

    • Most Recent Events

    • 29 Sep 2024 This trial has been completed in Denmark, as per European Clinical Trials Database record.
    • 30 May 2021 Planned End Date changed from 19 Feb 2025 to 20 Feb 2025.
    • 08 Dec 2020 Results (n=215) of the long-term outcomes after a 5-year follow-up from this study are presented at the 62nd Annual Meeting and Exposition of the American Society of Hematology

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