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Evaluation of Ruxolitinib and Azacytidine Combination as a Therapy for Patients With Myelofibrosis and Myelodysplastic Syndrome/ Myeloproliferative Neoplasm

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Trial Profile

Evaluation of Ruxolitinib and Azacytidine Combination as a Therapy for Patients With Myelofibrosis and Myelodysplastic Syndrome/ Myeloproliferative Neoplasm

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Oct 2024

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At a glance

  • Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Ruxolitinib (Primary)
  • Indications Chronic myeloid leukaemia; Chronic myelomonocytic leukaemia; Essential thrombocythaemia; Myelodysplastic syndromes; Myelofibrosis; Myeloproliferative disorders; Polycythaemia vera
  • Focus Therapeutic Use
  • Most Recent Events

    • 04 Jun 2024 Interim results(From 3/2013-10/2021, n=61 pts) evaluating ruxolitinib (RUX) and azacitidine (AZA) combination therapy , presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 12 Dec 2023 Results( data cutoff July 15, 2023 , n=52 ) evaluating the use of RUX-AZA in newly diagnosed or previously treated MDS/ MPN, presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 04 Apr 2023 Planned End Date changed from 1 Mar 2024 to 30 Apr 2025.

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