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A Phase 1, Open-label, Multiple-dose, Single Centre Study to Investigate the Effect of Administration of CAZ-AVI and CXL on the Intestinal Flora of Healthy Volunteers.

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Trial Profile

A Phase 1, Open-label, Multiple-dose, Single Centre Study to Investigate the Effect of Administration of CAZ-AVI and CXL on the Intestinal Flora of Healthy Volunteers.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Oct 2021

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At a glance

  • Drugs Avibactam/ceftaroline fosamil (Primary) ; Avibactam/ceftazidime (Primary)
  • Indications Bacterial infections; Gram-negative infections; Intra-abdominal infections; Methicillin-resistant Staphylococcus aureus infections; Nosocomial infections; Systemic inflammatory response syndrome; Urinary tract infections
  • Focus Pharmacodynamics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 02 Apr 2014 Status changed from recruiting to completed, as per ClinicalTrials.gov record.
    • 18 Feb 2014 Planned number of patients changed from 28 to 30, as per ClinicalTrials.gov record.
    • 18 Feb 2014 Planned End Date changed from 1 Jan 2014 to 1 Mar 2014, as per ClinicalTrials.gov record.

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